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Interações medicamentosas

Acrivastine + Butorphanol

Gravidade: Moderada

Acrivastine and Butorphanol: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Acrivastine is a relatively non-sedating antihistamine, but it can cause drowsiness in some patients. Combined with butorphanol, sedation and impaired concentration may be increased.

O que esta interação significa em palavras simples

Acrivastine and Butorphanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Acrivastine belongs to Respiratory; Butorphanol belongs to Musculoskeletal.

Nível de evidência: Low

Por que acontece

Additive central nervous system depression from opioid receptor activity and antihistamine H1 blockade.

O que fazer

Warn the patient about drowsiness and advise against driving until the response is known. Reduce the butorphanol dose or stop the antihistamine if sedation is excessive.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Acrivastine with Butorphanol?

MediHelp rates the interaction as moderate. Acrivastine and Butorphanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Acrivastine is a relatively non-sedating antihistamine, but it can cause drowsiness in some patients. Combined with butorphanol, sedation and impaired concentration may be increased.

How serious is the interaction between Acrivastine and Butorphanol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about drowsiness and advise against driving until the response is known. Reduce the butorphanol dose or stop the antihistamine if sedation is excessive.

What other medicines interact with Butorphanol?

MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.

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