Interações medicamentosas
Butorphanol + Sodium oxybate
Gravidade: Contraindicada
Butorphanol and Sodium oxybate: contraindicated interaction.
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Resumo
Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Labeling for sodium oxybate generally warns against use with other CNS depressants such as opioids.
O que esta interação significa em palavras simples
Butorphanol and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Butorphanol belongs to Musculoskeletal; Sodium oxybate belongs to Central Nervous System.
Por que acontece
Additive pharmacodynamic CNS and respiratory depression.
O que fazer
Avoid the combination. If an opioid is unavoidable, use the lowest dose for the shortest time, and monitor respiratory status and consciousness closely, with consideration of reducing or interrupting oxybate.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Butorphanol
- Butorphanol + Olanzapine / samidorphan Contraindicada
- Alfentanil + Butorphanol Grave
- Alprazolam + Butorphanol Grave
- Alvimopan + Butorphanol Grave
- Amobarbital + Butorphanol Grave
- Belladonna and opium + Butorphanol Grave
Outras interações de Sodium oxybate
- Alprazolam + Sodium oxybate Contraindicada
- Amobarbital + Sodium oxybate Contraindicada
- Chloral hydrate + Sodium oxybate Contraindicada
- Clonazepam + Sodium oxybate Contraindicada
- Clorazepate + Sodium oxybate Contraindicada
- Eszopiclone + Sodium oxybate Contraindicada
Perguntas frequentes
Can I take Butorphanol with Sodium oxybate?
MediHelp rates the interaction as contraindicated. Butorphanol and Sodium oxybate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs depress the central nervous system, and combining them can cause profound sedation, respiratory depression, coma and death. Labeling for sodium oxybate generally warns against use with other CNS depressants such as opioids.
How serious is the interaction between Butorphanol and Sodium oxybate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. If an opioid is unavoidable, use the lowest dose for the shortest time, and monitor respiratory status and consciousness closely, with consideration of reducing or interrupting oxybate.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Alfentanil, Alprazolam. The full list is on the Butorphanol page.
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