Interações medicamentosas
Adenovirus types 4 and 7 live + Daunorubicin
Gravidade: Contraindicada
Adenovirus types 4 and 7 live and Daunorubicin: contraindicated interaction.
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Resumo
Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
O que esta interação significa em palavras simples
Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression from the cytotoxic agent impairs the immune response and allows the live attenuated virus to replicate uncontrolled.
O que fazer
Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Daunorubicin
Perguntas frequentes
Can I take Adenovirus types 4 and 7 live with Daunorubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
How serious is the interaction between Adenovirus types 4 and 7 live and Daunorubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Belatacept, Cyclosporine, Cyclosporin. The full list is on the Daunorubicin page.
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