Interações medicamentosas
Almotriptan + Methylergonovine
Gravidade: Contraindicada
Almotriptan and Methylergonovine: contraindicated interaction.
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Resumo
Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
O que esta interação significa em palavras simples
Almotriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive vasoconstriction from ergot alkaloid and 5-HT1B/1D agonist effects.
O que fazer
Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Almotriptan
- Almotriptan + Dihydroergotamine Contraindicada
- Almotriptan + Dihydroergotamine intranasal Contraindicada
- Almotriptan + Eletriptan Contraindicada
- Almotriptan + Ergoloid mesylates Contraindicada
- Almotriptan + Ergotamine Contraindicada
- Almotriptan + Frovatriptan Contraindicada
Perguntas frequentes
Can I take Almotriptan with Methylergonovine?
MediHelp rates the interaction as contraindicated. Almotriptan and Methylergonovine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylergonovine is an ergot alkaloid with strong vasoconstrictor activity, and combining it with a triptan can cause prolonged vasospasm. This can lead to ischemia and hypertension.
How serious is the interaction between Almotriptan and Methylergonovine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use within 24 hours of each other. Use alternative uterotonic or migraine therapy.
What other medicines interact with Almotriptan?
MediHelp also lists interactions of Almotriptan with, for example, Dihydroergotamine, Dihydroergotamine intranasal, Eletriptan. The full list is on the Almotriptan page.
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