Interações medicamentosas
Almotriptan + Ergotamine
Gravidade: Contraindicada
Almotriptan and Ergotamine: contraindicated interaction.
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Resumo
Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
O que esta interação significa em palavras simples
Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Almotriptan belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
Por que acontece
Additive vasoconstriction (5-HT1B/1D agonism)
O que fazer
Separate the two by at least 24 hours or choose a single agent.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Almotriptan
- Almotriptan + Dihydroergotamine Contraindicada
- Almotriptan + Dihydroergotamine intranasal Contraindicada
- Almotriptan + Eletriptan Contraindicada
- Almotriptan + Ergoloid mesylates Contraindicada
- Almotriptan + Frovatriptan Contraindicada
- Almotriptan + Methylergonovine Contraindicada
Outras interações de Ergotamine
- Atazanavir + Ergotamine Contraindicada
- Clarithromycin + Ergotamine Contraindicada
- Cobicistat + Ergotamine Contraindicada
- Darunavir + Ergotamine Contraindicada
- Dihydroergotamine intranasal + Ergotamine Contraindicada
- Dihydroergotamine + Ergotamine Contraindicada
Perguntas frequentes
Can I take Almotriptan with Ergotamine?
MediHelp rates the interaction as contraindicated. Almotriptan and Ergotamine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and almotriptan both constrict vascular smooth muscle through serotonin receptors. Used in close succession they can cause sustained vasospasm with cerebral or limb ischaemia.
How serious is the interaction between Almotriptan and Ergotamine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the two by at least 24 hours or choose a single agent.
What other medicines interact with Almotriptan?
MediHelp also lists interactions of Almotriptan with, for example, Dihydroergotamine, Dihydroergotamine intranasal, Eletriptan. The full list is on the Almotriptan page.
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