Interações medicamentosas
Alprazolam + Brivaracetam
Gravidade: Moderada
Alprazolam and Brivaracetam: moderate interaction.
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Resumo
Brivaracetam commonly causes somnolence, dizziness and fatigue, and these effects may add to those of alprazolam. Patients may experience impaired alertness and coordination.
O que esta interação significa em palavras simples
Alprazolam and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alprazolam belongs to Central Nervous System; Brivaracetam belongs to Central Nervous System.
Por que acontece
Additive CNS depression; brivaracetam acts at SV2A while alprazolam enhances GABA-A activity.
O que fazer
Start brivaracetam at the lower end of the dose range and monitor for sedation and dizziness. Warn patients about driving and other tasks needing alertness.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contraindicada
- Alprazolam + Itraconazole Contraindicada
- Alprazolam + Ketoconazole Contraindicada
- Alprazolam + Levoketoconazole Contraindicada
- Alprazolam + Sodium oxybate Contraindicada
- Alfentanil + Alprazolam Grave
Outras interações de Brivaracetam
Perguntas frequentes
Can I take Alprazolam with Brivaracetam?
MediHelp rates the interaction as moderate. Alprazolam and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Brivaracetam commonly causes somnolence, dizziness and fatigue, and these effects may add to those of alprazolam. Patients may experience impaired alertness and coordination.
How serious is the interaction between Alprazolam and Brivaracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Start brivaracetam at the lower end of the dose range and monitor for sedation and dizziness. Warn patients about driving and other tasks needing alertness.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
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