Interações medicamentosas
Amobarbital + Brivaracetam
Gravidade: Moderada
Amobarbital and Brivaracetam: moderate interaction.
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Resumo
Both drugs depress the central nervous system, so taking them together can increase drowsiness, dizziness and impaired psychomotor performance. Barbiturates may also lower brivaracetam exposure through enzyme induction.
O que esta interação significa em palavras simples
Amobarbital and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amobarbital belongs to Central Nervous System; Brivaracetam belongs to Central Nervous System.
Por que acontece
Additive CNS depression; barbiturate-mediated enzyme induction may modestly reduce brivaracetam levels.
O que fazer
Monitor for excessive sedation and for loss of seizure control, and adjust the brivaracetam dose according to response. Warn patients against driving or operating machinery until the response is known.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amobarbital
- Amobarbital + Calcium / magnesium / potassium / sodium oxybates Contraindicada
- Amobarbital + Doravirine Contraindicada
- Amobarbital + Elbasvir / grazoprevir Contraindicada
- Amobarbital + Isavuconazonium Contraindicada
- Amobarbital + Isocarboxazid Contraindicada
- Amobarbital + Lonafarnib Contraindicada
Outras interações de Brivaracetam
Perguntas frequentes
Can I take Amobarbital with Brivaracetam?
MediHelp rates the interaction as moderate. Amobarbital and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs depress the central nervous system, so taking them together can increase drowsiness, dizziness and impaired psychomotor performance. Barbiturates may also lower brivaracetam exposure through enzyme induction.
How serious is the interaction between Amobarbital and Brivaracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation and for loss of seizure control, and adjust the brivaracetam dose according to response. Warn patients against driving or operating machinery until the response is known.
What other medicines interact with Amobarbital?
MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.
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