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Interações medicamentosas

Aminolevulinic acid + Amlodipine-olmesartan-hydrochlorothiazide

Gravidade: Moderada

Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Hydrochlorothiazide is a photosensitizing drug, and oral aminolevulinic acid causes photosensitivity used for imaging during surgery. Together they may increase the risk of phototoxic skin reactions.

O que esta interação significa em palavras simples

Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Aminolevulinic acid belongs to Miscellaneous; Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular.

Nível de evidência: Low

Por que acontece

Additive phototoxicity from two photosensitizing agents.

O que fazer

Avoid other photosensitizing drugs during the perioperative period of aminolevulinic acid use, and counsel on strict sun and bright light protection. Hold hydrochlorothiazide temporarily if clinically appropriate.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

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Perguntas frequentes

Can I take Aminolevulinic acid with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp rates the interaction as moderate. Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide is a photosensitizing drug, and oral aminolevulinic acid causes photosensitivity used for imaging during surgery. Together they may increase the risk of phototoxic skin reactions.

How serious is the interaction between Aminolevulinic acid and Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid other photosensitizing drugs during the perioperative period of aminolevulinic acid use, and counsel on strict sun and bright light protection. Hold hydrochlorothiazide temporarily if clinically appropriate.

What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?

MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.

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