Interações medicamentosas
Amlodipine-olmesartan-hydrochlorothiazide + Colesevelam
Gravidade: Moderada
Amlodipine-olmesartan-hydrochlorothiazide and Colesevelam: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Colesevelam can bind olmesartan in the gut and lower its absorption, possibly reducing blood pressure control. Binding of hydrochlorothiazide is also possible.
O que esta interação significa em palavras simples
Amlodipine-olmesartan-hydrochlorothiazide and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Colesevelam belongs to Endocrine.
Por que acontece
Bile acid sequestrant binds olmesartan in the gastrointestinal tract, reducing absorption.
O que fazer
Give the combination tablet at least 4 hours before colesevelam. Monitor blood pressure if dosing cannot be separated.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Amlodipine-olmesartan-hydrochlorothiazide e Colesevelam, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Contraindicada
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Contraindicada
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Contraindicada
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Grave
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Grave
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Grave
Outras interações de Colesevelam
- Amlodipine-olmesartan + Colesevelam Moderada
- Chenodiol + Colesevelam Moderada
- Cholic acid + Colesevelam Moderada
- Colesevelam + Cyclosporin Moderada
- Colesevelam + Cyclosporine Moderada
- Colesevelam + Gliclazide Moderada
Perguntas frequentes
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Colesevelam?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Colesevelam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colesevelam can bind olmesartan in the gut and lower its absorption, possibly reducing blood pressure control. Binding of hydrochlorothiazide is also possible.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Colesevelam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the combination tablet at least 4 hours before colesevelam. Monitor blood pressure if dosing cannot be separated.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
