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Interações medicamentosas

Amoxicillin + Cholera vaccine

Gravidade: Moderada

Amoxicillin and Cholera vaccine: moderate interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

The oral cholera vaccine is a live attenuated strain that can be killed by active antibiotics, which may reduce the immune response. Protection may therefore be inadequate.

O que esta interação significa em palavras simples

Amoxicillin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Moderate

Por que acontece

Antibacterial activity against the live attenuated Vibrio cholerae vaccine strain reduces its replication and immunogenicity.

O que fazer

Do not give the vaccine within 14 days of oral or parenteral antibiotic use, as per labeling. Delay vaccination until the antibiotic course is complete.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Amoxicillin with Cholera vaccine?

MediHelp rates the interaction as moderate. Amoxicillin and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral cholera vaccine is a live attenuated strain that can be killed by active antibiotics, which may reduce the immune response. Protection may therefore be inadequate.

How serious is the interaction between Amoxicillin and Cholera vaccine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the vaccine within 14 days of oral or parenteral antibiotic use, as per labeling. Delay vaccination until the antibiotic course is complete.

What other medicines interact with Amoxicillin?

MediHelp also lists interactions of Amoxicillin with, for example, Methotrexate, Bcg vaccine live, Eravacycline. The full list is on the Amoxicillin page.

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