Interações medicamentosas
Antithymocyte globulin rabbit + Echinacea
Gravidade: Moderada
Antithymocyte globulin rabbit and Echinacea: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
O que esta interação significa em palavras simples
Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Theoretical pharmacodynamic antagonism between herbal immune stimulation and profound T-cell depletion.
O que fazer
Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Echinacea
- Alefacept + Echinacea Moderada
- Antithymocyte globulin equine + Echinacea Moderada
- Azathioprine + Echinacea Moderada
- Basiliximab + Echinacea Moderada
- Cyclosporine + Echinacea Moderada
- Cyclosporin + Echinacea Moderada
Perguntas frequentes
Can I take Antithymocyte globulin rabbit with Echinacea?
MediHelp rates the interaction as moderate. Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
How serious is the interaction between Antithymocyte globulin rabbit and Echinacea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Azathioprine. The full list is on the Echinacea page.
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