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Interações medicamentosas

Azathioprine + Echinacea

Gravidade: Moderada

Azathioprine and Echinacea: moderate interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Echinacea has immunostimulant properties that could theoretically oppose the immunosuppressive effect of azathioprine. This could reduce disease control or graft protection, although clinical data are lacking.

O que esta interação significa em palavras simples

Azathioprine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Azathioprine belongs to Gastrointestinal Tract; Echinacea belongs to Gastrointestinal Tract.

Nível de evidência: Low

Por que acontece

Theoretical pharmacodynamic antagonism between immune stimulation by echinacea and immunosuppression by azathioprine; not well established.

O que fazer

Advise patients on azathioprine to avoid echinacea products. If used, monitor for loss of disease control or signs of graft rejection.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Azathioprine with Echinacea?

MediHelp rates the interaction as moderate. Azathioprine and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea has immunostimulant properties that could theoretically oppose the immunosuppressive effect of azathioprine. This could reduce disease control or graft protection, although clinical data are lacking.

How serious is the interaction between Azathioprine and Echinacea?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients on azathioprine to avoid echinacea products. If used, monitor for loss of disease control or signs of graft rejection.

What other medicines interact with Azathioprine?

MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.

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