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Interações medicamentosas

Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent

Gravidade: Moderada

Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent: moderate interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Rabbit antithymocyte globulin causes prolonged T-cell depletion and may diminish the antibody response to pneumococcal conjugate vaccine. The vaccine itself is safe.

O que esta interação significa em palavras simples

Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Nível de evidência: Moderate

Por que acontece

Prolonged lymphocyte depletion impairs T-cell-dependent antibody production.

O que fazer

Postpone elective vaccination until immune reconstitution; if given earlier, assess antibody response and revaccinate if needed.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Antithymocyte globulin rabbit with Pneumococcal vaccine 13-valent?

MediHelp rates the interaction as moderate. Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rabbit antithymocyte globulin causes prolonged T-cell depletion and may diminish the antibody response to pneumococcal conjugate vaccine. The vaccine itself is safe.

How serious is the interaction between Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Postpone elective vaccination until immune reconstitution; if given earlier, assess antibody response and revaccinate if needed.

What other medicines interact with Pneumococcal vaccine 13-valent?

MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.

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