Drug interactions
Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent
Severity: Moderate
Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rabbit antithymocyte globulin causes prolonged T-cell depletion and may diminish the antibody response to pneumococcal conjugate vaccine. The vaccine itself is safe.
What this interaction means in plain words
Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Prolonged lymphocyte depletion impairs T-cell-dependent antibody production.
What to do
Postpone elective vaccination until immune reconstitution; if given earlier, assess antibody response and revaccinate if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent Moderate
- Atidarsagene autotemcel + Pneumococcal vaccine 13-valent Moderate
Frequently asked questions
Can I take Antithymocyte globulin rabbit with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as moderate. Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rabbit antithymocyte globulin causes prolonged T-cell depletion and may diminish the antibody response to pneumococcal conjugate vaccine. The vaccine itself is safe.
How serious is the interaction between Antithymocyte globulin rabbit and Pneumococcal vaccine 13-valent?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Postpone elective vaccination until immune reconstitution; if given earlier, assess antibody response and revaccinate if needed.
What other medicines interact with Pneumococcal vaccine 13-valent?
MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.
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