Interações medicamentosas
Azathioprine + Measles mumps and rubella vaccine
Gravidade: Contraindicada
Azathioprine and Measles mumps and rubella vaccine: contraindicated interaction.
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Resumo
The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
O que esta interação significa em palavras simples
Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Azathioprine belongs to Gastrointestinal Tract; Measles mumps and rubella vaccine belongs to Miscellaneous.
Por que acontece
Azathioprine-mediated immunosuppression allows replication of a live attenuated virus
O que fazer
Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicada
- Anakinra + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicada
- Basiliximab + Measles mumps and rubella vaccine Contraindicada
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicada
Outras interações de Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Contraindicada
- Azathioprine + Bcg vaccine live Contraindicada
- Azathioprine + Febuxostat Contraindicada
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Azathioprine + Measles mumps and rubella vaccine live Contraindicada
- Azathioprine + Measles mumps rubella and varicella vaccine live Contraindicada
Perguntas frequentes
Can I take Azathioprine with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Azathioprine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated vaccine relies on a competent immune system to limit viral replication, and azathioprine (a purine-antimetabolite immunosuppressant) weakens that control. Disseminated vaccine-strain infection is possible and the antibody response to the vaccine may also be reduced.
How serious is the interaction between Azathioprine and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment; where possible, vaccinate at least 4 weeks before starting the immunosuppressant, and delay after stopping until immune function has recovered.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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