Interações medicamentosas
Azelaic acid + Urea
Gravidade: Leve
Azelaic acid and Urea: minor interaction.
Última atualização Fontes: US FDA label
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
O que esta interação significa em palavras simples
Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Azelaic acid belongs to Dermatology; Urea belongs to Miscellaneous.
Por que acontece
Additive local irritation, with urea's keratolytic and hydrating action possibly increasing penetration of azelaic acid.
O que fazer
If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
O que perguntar ao farmacêutico
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Referências
Outras interações de Azelaic acid
Outras interações de Urea
- Tretinoin + Urea Leve
Perguntas frequentes
Can I take Azelaic acid with Urea?
MediHelp rates the interaction as minor. Azelaic acid and Urea have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Co-application may increase local irritation such as stinging, burning and dryness. Urea can disrupt the stratum corneum and may increase skin penetration of other topical agents. The effect is usually mild and is more likely at higher urea strengths or on damaged skin.
How serious is the interaction between Azelaic acid and Urea?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If both are needed, apply them at different times of day or on alternate days and avoid broken skin. Start with low-strength urea and monitor for irritation.
What other medicines interact with Azelaic acid?
MediHelp also lists interactions of Azelaic acid with, for example, Tretinoin. The full list is on the Azelaic acid page.
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