Interações medicamentosas
Belimumab + Measles mumps and rubella vaccine
Gravidade: Grave
Belimumab and Measles mumps and rubella vaccine: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
O que esta interação significa em palavras simples
Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Belimumab belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Por que acontece
Inhibition of BLyS reduces B-cell activity, which may blunt vaccine response and impair control of live attenuated viruses.
O que fazer
Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicada
- Anakinra + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicada
- Azathioprine + Measles mumps and rubella vaccine Contraindicada
- Basiliximab + Measles mumps and rubella vaccine Contraindicada
Outras interações de Belimumab
- Abatacept + Belimumab Moderada
- Adalimumab + Belimumab Moderada
- Anakinra + Belimumab Moderada
- Anti-thymocyte + Belimumab Moderada
- Belimumab + Denosumab Moderada
- Belimumab + Fingolimod Moderada
Perguntas frequentes
Can I take Belimumab with Measles mumps and rubella vaccine?
MediHelp rates the interaction as major. Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
How serious is the interaction between Belimumab and Measles mumps and rubella vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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