Interações medicamentosas
Belladonna and opium + Glycopyrronium
Gravidade: Moderada
Belladonna and opium and Glycopyrronium: moderate interaction.
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Resumo
Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
O que esta interação significa em palavras simples
Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive antimuscarinic effects, with opioid-induced reduction of gut and bladder motility compounding them.
O que fazer
Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Glycopyrronium
- Clozapine + Glycopyrronium Grave
- Abobotulinumtoxina + Glycopyrronium Moderada
- Aclidinium + Glycopyrronium Moderada
- Amantadine + Glycopyrronium Moderada
- Amitriptyline + Glycopyrronium Moderada
- Amoxapine + Glycopyrronium Moderada
Perguntas frequentes
Can I take Belladonna and opium with Glycopyrronium?
MediHelp rates the interaction as moderate. Belladonna and opium and Glycopyrronium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna and opium suppositories combine an antimuscarinic with an opioid, and with glycopyrronium the anticholinergic and constipating effects add up. Urinary retention, severe constipation and paralytic ileus can result.
How serious is the interaction between Belladonna and opium and Glycopyrronium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor bowel function and urinary output, and avoid the combination in patients with ileus risk or urinary obstruction.
What other medicines interact with Glycopyrronium?
MediHelp also lists interactions of Glycopyrronium with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Glycopyrronium page.
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