Interações medicamentosas
Calcium gluconate + Ceftriaxone
Gravidade: Contraindicada
Calcium gluconate and Ceftriaxone: contraindicated interaction.
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Resumo
Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
O que esta interação significa em palavras simples
Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Calcium gluconate belongs to Gastrointestinal Tract; Ceftriaxone belongs to Anti Bacterial.
Por que acontece
Ceftriaxone binds calcium to form poorly soluble ceftriaxone-calcium precipitate.
O que fazer
Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Ceftriaxone
- Calcium chloride + Ceftriaxone Contraindicada
- Calcium + Ceftriaxone Contraindicada
- Ceftriaxone + Lactated ringer's Contraindicada
- Ceftriaxone + Ringer's solution Contraindicada
- Calcium acetate + Ceftriaxone Grave
- Ceftriaxone + Lactated Ringer's solution Grave
Outras interações de Calcium gluconate
- Calcium gluconate + Digoxin Grave
- Alendronate + Calcium gluconate Moderada
- Amlodipine-atorvastatin + Calcium gluconate Moderada
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderada
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderada
- Amlodipine-perindopril + Calcium gluconate Moderada
Perguntas frequentes
Can I take Calcium gluconate with Ceftriaxone?
MediHelp rates the interaction as contraindicated. Calcium gluconate and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone can form insoluble ceftriaxone-calcium salts when it meets calcium-containing solutions. Fatal cases have occurred in neonates with crystalline deposits in the lungs and kidneys. Precipitation can also occur in the infusion line or in the body after separate infusions.
How serious is the interaction between Calcium gluconate and Ceftriaxone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Never mix or co-infuse ceftriaxone with calcium-containing IV solutions, and in neonates avoid concurrent use entirely. In patients older than 28 days, give sequentially only with thorough line flushing between infusions using a compatible fluid.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium chloride, Calcium, Lactated ringer's. The full list is on the Ceftriaxone page.
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