Interações medicamentosas
Amlodipine-perindopril + Calcium gluconate
Gravidade: Moderada
Amlodipine-perindopril and Calcium gluconate: moderate interaction.
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Resumo
Intravenous calcium gluconate can counteract calcium channel blocker effects and is used to treat overdose. In patients on amlodipine it may reduce the blood pressure lowering effect, but oral use rarely matters.
O que esta interação significa em palavras simples
Amlodipine-perindopril and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-perindopril belongs to Cardiovascular; Calcium gluconate belongs to Gastrointestinal Tract.
Por que acontece
Pharmacodynamic antagonism, because increased extracellular calcium overcomes L-type channel blockade.
O que fazer
Monitor blood pressure and heart rate during parenteral calcium administration. For oral supplements, monitor serum calcium only.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Amlodipine-perindopril
- Aliskiren + Amlodipine-perindopril Contraindicada
- Amlodipine-perindopril + Protein a column Contraindicada
- Amlodipine-perindopril + Sacubitril / valsartan Contraindicada
- Amifostine + Amlodipine-perindopril Grave
- Amiloride + Amlodipine-perindopril Grave
- Amlodipine-perindopril + Azilsartan Grave
Outras interações de Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicada
- Calcium gluconate + Digoxin Grave
- Alendronate + Calcium gluconate Moderada
- Amlodipine-atorvastatin + Calcium gluconate Moderada
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderada
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderada
Perguntas frequentes
Can I take Amlodipine-perindopril with Calcium gluconate?
MediHelp rates the interaction as moderate. Amlodipine-perindopril and Calcium gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravenous calcium gluconate can counteract calcium channel blocker effects and is used to treat overdose. In patients on amlodipine it may reduce the blood pressure lowering effect, but oral use rarely matters.
How serious is the interaction between Amlodipine-perindopril and Calcium gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during parenteral calcium administration. For oral supplements, monitor serum calcium only.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.
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