Interações medicamentosas
Calcium gluconate + Etidronate
Gravidade: Moderada
Calcium gluconate and Etidronate: moderate interaction.
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Resumo
Oral calcium gluconate can bind etidronate in the gut and reduce its absorption. The result may be diminished efficacy of the bisphosphonate.
O que esta interação significa em palavras simples
Calcium gluconate and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium gluconate belongs to Gastrointestinal Tract; Etidronate belongs to Musculoskeletal.
Por que acontece
Divalent calcium cations chelate etidronate in the gastrointestinal tract, forming poorly absorbable complexes.
O que fazer
Keep oral calcium gluconate at least 2 hours apart from etidronate, which should be taken fasting. Intravenous calcium gluconate is not affected by this mechanism.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Etidronate
- Aluminum hydroxide + Etidronate Moderada
- Calcium acetate + Etidronate Moderada
- Calcium carbonate + Etidronate Moderada
- Calcium chloride + Etidronate Moderada
- Calcium citrate + Etidronate Moderada
- Calcium + Etidronate Moderada
Outras interações de Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicada
- Calcium gluconate + Digoxin Grave
- Alendronate + Calcium gluconate Moderada
- Amlodipine-atorvastatin + Calcium gluconate Moderada
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderada
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderada
Perguntas frequentes
Can I take Calcium gluconate with Etidronate?
MediHelp rates the interaction as moderate. Calcium gluconate and Etidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium gluconate can bind etidronate in the gut and reduce its absorption. The result may be diminished efficacy of the bisphosphonate.
How serious is the interaction between Calcium gluconate and Etidronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep oral calcium gluconate at least 2 hours apart from etidronate, which should be taken fasting. Intravenous calcium gluconate is not affected by this mechanism.
What other medicines interact with Etidronate?
MediHelp also lists interactions of Etidronate with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Etidronate page.
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