Interações medicamentosas
Calcium / magnesium / potassium / sodium oxybates + Chloral hydrate
Gravidade: Contraindicada
Calcium / magnesium / potassium / sodium oxybates and Chloral hydrate: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Both agents depress the central nervous system, and together they can cause profound sedation, respiratory depression, coma, or death. Oxybate labeling prohibits use with sedative hypnotics.
O que esta interação significa em palavras simples
Calcium / magnesium / potassium / sodium oxybates and Chloral hydrate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive CNS and respiratory depression through pharmacodynamic synergism (GABAergic sedative plus GHB-receptor and GABA-B agonism).
O que fazer
Do not combine; stop chloral hydrate or use a non-sedating alternative before starting oxybate therapy.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Calcium / magnesium / potassium / sodium oxybates e Chloral hydrate, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Chloral hydrate
Perguntas frequentes
Can I take Calcium / magnesium / potassium / sodium oxybates with Chloral hydrate?
MediHelp rates the interaction as contraindicated. Calcium / magnesium / potassium / sodium oxybates and Chloral hydrate are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents depress the central nervous system, and together they can cause profound sedation, respiratory depression, coma, or death. Oxybate labeling prohibits use with sedative hypnotics.
How serious is the interaction between Calcium / magnesium / potassium / sodium oxybates and Chloral hydrate?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; stop chloral hydrate or use a non-sedating alternative before starting oxybate therapy.
What other medicines interact with Chloral hydrate?
MediHelp also lists interactions of Chloral hydrate with, for example, Sodium oxybate, Alfentanil, Alprazolam. The full list is on the Chloral hydrate page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
