Interações medicamentosas
Cefadroxil + Kanamycin
Gravidade: Moderada
Cefadroxil and Kanamycin: moderate interaction.
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Resumo
Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been reported to add to renal injury when combined with them. Cefadroxil has little intrinsic nephrotoxicity, so the added risk is modest but matters in patients with reduced renal function. Both drugs are renally eliminated, so impairment raises exposure to each.
O que esta interação significa em palavras simples
Cefadroxil and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Additive renal tubular injury, with reduced renal clearance of both drugs when kidney function declines.
O que fazer
Monitor serum creatinine and aminoglycoside levels, and adjust doses to renal function. Ensure hydration and watch for hearing or balance changes.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefadroxil
- Amikacin + Cefadroxil Moderada
- Avelumab + Cefadroxil Moderada
- Balstilimab + Cefadroxil Moderada
- Bcg vaccine live + Cefadroxil Moderada
- Cefadroxil + Cholera vaccine Moderada
- Cefadroxil + Gentamicin Moderada
Perguntas frequentes
Can I take Cefadroxil with Kanamycin?
MediHelp rates the interaction as moderate. Cefadroxil and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been reported to add to renal injury when combined with them. Cefadroxil has little intrinsic nephrotoxicity, so the added risk is modest but matters in patients with reduced renal function. Both drugs are renally eliminated, so impairment raises exposure to each.
How serious is the interaction between Cefadroxil and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and aminoglycoside levels, and adjust doses to renal function. Ensure hydration and watch for hearing or balance changes.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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