Interações medicamentosas
Cefditoren + Kanamycin
Gravidade: Moderada
Cefditoren and Kanamycin: moderate interaction.
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Resumo
Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additive kidney injury when combined with them. The effect is mainly reported with parenteral aminoglycosides in patients with other risk factors.
O que esta interação significa em palavras simples
Cefditoren and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Possible additive nephrotoxicity; the aminoglycoside itself causes proximal tubular and cochlear toxicity.
O que fazer
Monitor serum creatinine and aminoglycoside levels, keep the patient well hydrated, and adjust doses for renal function.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefditoren
- Aluminum hydroxide + Cefditoren Moderada
- Calcium carbonate + Cefditoren Moderada
- Calcium + Cefditoren Moderada
- Cefditoren + Cholera vaccine Moderada
- Cefditoren + Cimetidine Moderada
- Cefditoren + Dexlansoprazole Moderada
Perguntas frequentes
Can I take Cefditoren with Kanamycin?
MediHelp rates the interaction as moderate. Cefditoren and Kanamycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additive kidney injury when combined with them. The effect is mainly reported with parenteral aminoglycosides in patients with other risk factors.
How serious is the interaction between Cefditoren and Kanamycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and aminoglycoside levels, keep the patient well hydrated, and adjust doses for renal function.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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