Interações medicamentosas
Chlorpromazine + Tretinoin
Gravidade: Moderada
Chlorpromazine and Tretinoin: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Chlorpromazine is a well-known photosensitizer, and systemic tretinoin also increases skin sensitivity to ultraviolet light. Together they may cause exaggerated sunburn-like or phototoxic reactions.
O que esta interação significa em palavras simples
Chlorpromazine and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpromazine belongs to Central Nervous System; Tretinoin belongs to Dermatology.
Por que acontece
Additive phototoxicity through different photosensitizing mechanisms.
O que fazer
Counsel patients to use strict sun protection with broad-spectrum sunscreen and protective clothing. Review the skin if a reaction develops.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Chlorpromazine
- Chlorpromazine + Dofetilide Contraindicada
- Chlorpromazine + Dronedarone Contraindicada
- Chlorpromazine + Droperidol Contraindicada
- Chlorpromazine + Ibutilide Contraindicada
- Chlorpromazine + Metrizamide Contraindicada
- Chlorpromazine + Panobinostat Contraindicada
Outras interações de Tretinoin
- Doxycycline + Tretinoin Grave
- Minocycline + Tretinoin Grave
- Omadacycline + Tretinoin Grave
- Palovarotene + Tretinoin Grave
- Sarecycline + Tretinoin Grave
- Tetracycline + Tretinoin Grave
Perguntas frequentes
Can I take Chlorpromazine with Tretinoin?
MediHelp rates the interaction as moderate. Chlorpromazine and Tretinoin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlorpromazine is a well-known photosensitizer, and systemic tretinoin also increases skin sensitivity to ultraviolet light. Together they may cause exaggerated sunburn-like or phototoxic reactions.
How serious is the interaction between Chlorpromazine and Tretinoin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to use strict sun protection with broad-spectrum sunscreen and protective clothing. Review the skin if a reaction develops.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
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