Interações medicamentosas
Ciprofloxacin + Ferrous gluconate
Gravidade: Grave
Ciprofloxacin and Ferrous gluconate: major interaction.
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Resumo
Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
O que esta interação significa em palavras simples
Ciprofloxacin and Ferrous gluconate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Ferrous gluconate belongs to Miscellaneous.
Por que acontece
Ferrous iron chelates ciprofloxacin in the gastrointestinal tract, forming poorly absorbed complexes.
O que fazer
Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicada
- Ciprofloxacin + Fezolinetant Contraindicada
- Ciprofloxacin + Thioridazine Contraindicada
- Ciprofloxacin + Tizanidine Contraindicada
- Ciprofloxacin + Vandetanib Contraindicada
- Alosetron + Ciprofloxacin Grave
Outras interações de Ferrous gluconate
- Acetohydroxamic acid + Ferrous gluconate Moderada
- Aluminum hydroxide + Ferrous gluconate Moderada
- Baloxavir marboxil + Ferrous gluconate Moderada
- Bictegravir + Ferrous gluconate Moderada
- Calcium carbonate + Ferrous gluconate Moderada
- Calcium + Ferrous gluconate Moderada
Perguntas frequentes
Can I take Ciprofloxacin with Ferrous gluconate?
MediHelp rates the interaction as major. Ciprofloxacin and Ferrous gluconate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
How serious is the interaction between Ciprofloxacin and Ferrous gluconate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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