Interações medicamentosas
Bictegravir + Ferrous gluconate
Gravidade: Moderada
Bictegravir and Ferrous gluconate: moderate interaction.
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Resumo
Iron binds bictegravir in the gut and can lower its exposure when taken fasting. Reduced levels may lead to loss of HIV virologic suppression or resistance.
O que esta interação significa em palavras simples
Bictegravir and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Iron cations chelate bictegravir in the gastrointestinal tract, reducing absorption.
O que fazer
Take bictegravir and iron together with food, or take bictegravir at least 2 hours before iron when fasting. Do not take iron within 2 hours before bictegravir on an empty stomach.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ferrous gluconate
Perguntas frequentes
Can I take Bictegravir with Ferrous gluconate?
MediHelp rates the interaction as moderate. Bictegravir and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds bictegravir in the gut and can lower its exposure when taken fasting. Reduced levels may lead to loss of HIV virologic suppression or resistance.
How serious is the interaction between Bictegravir and Ferrous gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir and iron together with food, or take bictegravir at least 2 hours before iron when fasting. Do not take iron within 2 hours before bictegravir on an empty stomach.
What other medicines interact with Ferrous gluconate?
MediHelp also lists interactions of Ferrous gluconate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous gluconate page.
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