Interações medicamentosas
Ciprofloxacin + Magnesium citrate
Gravidade: Grave
Ciprofloxacin and Magnesium citrate: major interaction.
Última atualização Fontes: UK SmPC
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Magnesium chelates ciprofloxacin in the gut and markedly reduces its absorption. This can cause subtherapeutic antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Ciprofloxacin and Magnesium citrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Magnesium citrate belongs to Gastrointestinal Tract.
Por que acontece
Chelation of ciprofloxacin by polyvalent magnesium cations in the gastrointestinal tract reduces absorption.
O que fazer
Give oral ciprofloxacin at least 2 hours before or 6 hours after magnesium citrate. Avoid the combination if separation is impractical.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Ciprofloxacin e Magnesium citrate, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 7 dias na web. Sem cartão.
Referências
- Ciprofloxacin 250mg film-coated tablets - SmPC sections 4.3/4.5 (class statement: multivalent cation-containing drugs and mineral supplements; "The simultaneous administration of ciprofloxacin (oral) and multivalent cation-containing drugs and mineral supplements (e.g. calcium, magnesium, aluminiu… — electronic medicines compendium (UK SmPC)
Outras interações de Magnesium citrate
- Baloxavir marboxil + Magnesium citrate Moderada
- Bictegravir + Magnesium citrate Moderada
- Cabotegravir + Magnesium citrate Moderada
- Cholecalciferol + Magnesium citrate Moderada
- Deferiprone + Magnesium citrate Moderada
- Demeclocycline + Magnesium citrate Moderada
Outras interações de Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicada
- Ciprofloxacin + Fezolinetant Contraindicada
- Ciprofloxacin + Thioridazine Contraindicada
- Ciprofloxacin + Tizanidine Contraindicada
- Ciprofloxacin + Vandetanib Contraindicada
- Alosetron + Ciprofloxacin Grave
Perguntas frequentes
Can I take Ciprofloxacin with Magnesium citrate?
MediHelp rates the interaction as major. Ciprofloxacin and Magnesium citrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium chelates ciprofloxacin in the gut and markedly reduces its absorption. This can cause subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Ciprofloxacin and Magnesium citrate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after magnesium citrate. Avoid the combination if separation is impractical.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Baloxavir marboxil, Bictegravir, Cabotegravir. The full list is on the Magnesium citrate page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
