Interações medicamentosas
Deferiprone + Interferon beta 1a
Gravidade: Grave
Deferiprone and Interferon beta 1a: major interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Deferiprone can cause neutropenia and agranulocytosis, and interferon beta can also lower white cell counts. Combined use may increase the risk of severe neutropenia and serious infection.
O que esta interação significa em palavras simples
Deferiprone and Interferon beta 1a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Interferon beta 1a belongs to Central Nervous System.
Por que acontece
Additive myelosuppressive effects on neutrophils.
O que fazer
Avoid the combination if an alternative exists. If both are necessary, monitor absolute neutrophil count more often than usual and stop deferiprone if neutropenia develops.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Interferon beta 1a
Outras interações de Deferiprone
- Clozapine + Deferiprone Contraindicada
- Abemaciclib + Deferiprone Grave
- Acalabrutinib + Deferiprone Grave
- Ado-trastuzumab emtansine + Deferiprone Grave
- Ado-trastuzumab + Deferiprone Grave
- Aldesleukin + Deferiprone Grave
Perguntas frequentes
Can I take Deferiprone with Interferon beta 1a?
MediHelp rates the interaction as major. Deferiprone and Interferon beta 1a can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause neutropenia and agranulocytosis, and interferon beta can also lower white cell counts. Combined use may increase the risk of severe neutropenia and serious infection.
How serious is the interaction between Deferiprone and Interferon beta 1a?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if an alternative exists. If both are necessary, monitor absolute neutrophil count more often than usual and stop deferiprone if neutropenia develops.
What other medicines interact with Interferon beta 1a?
MediHelp also lists interactions of Interferon beta 1a with, for example, Etrasimod, Hydroxyurea, Idecabtagene vicleucel. The full list is on the Interferon beta 1a page.
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