Interações medicamentosas
Dextroamphetamine + Linezolid
Gravidade: Contraindicada
Dextroamphetamine and Linezolid: contraindicated interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Linezolid inhibits catecholamine breakdown and enlarges neuronal norepinephrine stores, and dextroamphetamine releases norepinephrine and dopamine from nerve terminals. The result can be a hypertensive crisis with severe headache, arrhythmia, hyperpyrexia and intracranial haemorrhage.
O que esta interação significa em palavras simples
Dextroamphetamine and Linezolid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dextroamphetamine belongs to Central Nervous System; Linezolid belongs to Anti Bacterial.
Por que acontece
MAO inhibition plus indirect sympathomimetic norepinephrine release -> exaggerated pressor response
O que fazer
Do not give dextroamphetamine during or within 14 days of an MAO inhibitor; if the oxazolidinone is unavoidable, use only with intensive blood-pressure monitoring and avoid the stimulant.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Dextroamphetamine e Linezolid, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Linezolid
- Amoxapine + Linezolid Contraindicada
- Atomoxetine + Linezolid Contraindicada
- Benzphetamine + Linezolid Contraindicada
- Brimonidine + Linezolid Contraindicada
- Bupropion-naltrexone + Linezolid Contraindicada
- Bupropion + Linezolid Contraindicada
Outras interações de Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicada
- Dextroamphetamine + Methylene blue Contraindicada
- Dextroamphetamine + Phenelzine Contraindicada
- Dextroamphetamine + Rasagiline Contraindicada
- Dextroamphetamine + Safinamide Contraindicada
- Dextroamphetamine + Selegiline Contraindicada
Perguntas frequentes
Can I take Dextroamphetamine with Linezolid?
MediHelp rates the interaction as contraindicated. Dextroamphetamine and Linezolid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Linezolid inhibits catecholamine breakdown and enlarges neuronal norepinephrine stores, and dextroamphetamine releases norepinephrine and dopamine from nerve terminals. The result can be a hypertensive crisis with severe headache, arrhythmia, hyperpyrexia and intracranial haemorrhage.
How serious is the interaction between Dextroamphetamine and Linezolid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give dextroamphetamine during or within 14 days of an MAO inhibitor; if the oxazolidinone is unavoidable, use only with intensive blood-pressure monitoring and avoid the stimulant.
What other medicines interact with Linezolid?
MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
