Interações medicamentosas
Dihydroergotamine intranasal + Naratriptan
Gravidade: Contraindicada
Dihydroergotamine intranasal and Naratriptan: contraindicated interaction.
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Resumo
Intranasal dihydroergotamine reaches the circulation and, with naratriptan, may cause additive and prolonged vasospasm and ischemic events.
O que esta interação significa em palavras simples
Dihydroergotamine intranasal and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects.
O que fazer
Avoid the combination; separate by at least 24 hours. Use a single agent per attack.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Naratriptan
- Almotriptan + Naratriptan Contraindicada
- Dihydroergotamine + Naratriptan Contraindicada
- Eletriptan + Naratriptan Contraindicada
- Ergoloid mesylates + Naratriptan Contraindicada
- Ergotamine + Naratriptan Contraindicada
- Frovatriptan + Naratriptan Contraindicada
Perguntas frequentes
Can I take Dihydroergotamine intranasal with Naratriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine intranasal and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Intranasal dihydroergotamine reaches the circulation and, with naratriptan, may cause additive and prolonged vasospasm and ischemic events.
How serious is the interaction between Dihydroergotamine intranasal and Naratriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; separate by at least 24 hours. Use a single agent per attack.
What other medicines interact with Naratriptan?
MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine, Eletriptan. The full list is on the Naratriptan page.
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