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Interações medicamentosas

Ergotamine + Naratriptan

Gravidade: Contraindicada

Ergotamine and Naratriptan: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

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Resumo

Ergotamine and naratriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.

O que esta interação significa em palavras simples

Ergotamine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Ergotamine belongs to Central Nervous System; Naratriptan belongs to Central Nervous System.

Nível de evidência: High

Por que acontece

Additive vasoconstriction through serotonin receptors

O que fazer

Do not administer within 24 hours of each other.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Ergotamine with Naratriptan?

MediHelp rates the interaction as contraindicated. Ergotamine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and naratriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.

How serious is the interaction between Ergotamine and Naratriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.

What other medicines interact with Naratriptan?

MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.

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