Interações medicamentosas
Dimercaprol + Ferrous sulfate
Gravidade: Grave
Dimercaprol and Ferrous sulfate: major interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.
O que esta interação significa em palavras simples
Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Por que acontece
Dimercaprol forms a chelate with iron that is toxic and may worsen toxicity rather than promoting safe elimination.
O que fazer
Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.
O que perguntar ao farmacêutico
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Outras interações de Ferrous sulfate
Perguntas frequentes
Can I take Dimercaprol with Ferrous sulfate?
MediHelp rates the interaction as major. Dimercaprol and Ferrous sulfate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dimercaprol forms toxic complexes with iron and is not recommended in iron poisoning. The resulting iron-dimercaprol complex can be harmful to the kidneys and is of no benefit for iron removal. Oral iron should not be given with dimercaprol during chelation therapy.
How serious is the interaction between Dimercaprol and Ferrous sulfate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use dimercaprol to treat iron overload or iron poisoning; use deferoxamine instead. Hold iron supplements while dimercaprol is being given.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous sulfate page.
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