Interações medicamentosas
Baloxavir marboxil + Ferrous sulfate
Gravidade: Moderada
Baloxavir marboxil and Ferrous sulfate: moderate interaction.
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Resumo
Baloxavir can bind to polyvalent cations such as iron in the gut, which may lower its absorption and reduce plasma exposure. This could weaken antiviral effect during influenza treatment or prophylaxis. Supporting data come mainly from animal studies.
O que esta interação significa em palavras simples
Baloxavir marboxil and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Ferrous sulfate belongs to Miscellaneous.
Por que acontece
Chelation of baloxavir by iron in the gastrointestinal tract reduces its oral absorption.
O que fazer
Avoid taking oral iron products at the same time as baloxavir; if iron is required, give baloxavir at a different time than the iron dose, or use an alternative antiviral if separation is not feasible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Ferrous sulfate
Outras interações de Baloxavir marboxil
- Aluminum hydroxide + Baloxavir marboxil Moderada
- Baloxavir marboxil + Calcium Moderada
- Baloxavir marboxil + Calcium carbonate Moderada
- Baloxavir marboxil + Carbonyl iron Moderada
- Baloxavir marboxil + Ferrous fumarate Moderada
- Baloxavir marboxil + Ferrous gluconate Moderada
Perguntas frequentes
Can I take Baloxavir marboxil with Ferrous sulfate?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Ferrous sulfate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Baloxavir can bind to polyvalent cations such as iron in the gut, which may lower its absorption and reduce plasma exposure. This could weaken antiviral effect during influenza treatment or prophylaxis. Supporting data come mainly from animal studies.
How serious is the interaction between Baloxavir marboxil and Ferrous sulfate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking oral iron products at the same time as baloxavir; if iron is required, give baloxavir at a different time than the iron dose, or use an alternative antiviral if separation is not feasible.
What other medicines interact with Ferrous sulfate?
MediHelp also lists interactions of Ferrous sulfate with, for example, Ciprofloxacin, Dimercaprol, Acetohydroxamic acid. The full list is on the Ferrous sulfate page.
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