Interações medicamentosas
Everolimus + Measles mumps and rubella vaccine live
Gravidade: Contraindicada
Everolimus and Measles mumps and rubella vaccine live: contraindicated interaction.
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Resumo
This live attenuated vaccine can cause disseminated vaccine-strain infection in patients immunosuppressed by everolimus, and the immune response may also be reduced.
O que esta interação significa em palavras simples
Everolimus and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Immunosuppression from mTOR inhibition impairs control of live attenuated virus replication and reduces vaccine response.
O que fazer
Do not administer during everolimus therapy. Give at least several weeks before starting everolimus where feasible, and check immunity serologically if exposure occurs.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Everolimus
- Bcg vaccine live + Everolimus Contraindicada
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Everolimus + Levoketoconazole Contraindicada
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicada
- Everolimus + Measles vaccine Contraindicada
- Everolimus + Ritonavir Contraindicada
Perguntas frequentes
Can I take Everolimus with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Everolimus and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated vaccine can cause disseminated vaccine-strain infection in patients immunosuppressed by everolimus, and the immune response may also be reduced.
How serious is the interaction between Everolimus and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during everolimus therapy. Give at least several weeks before starting everolimus where feasible, and check immunity serologically if exposure occurs.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Levoketoconazole. The full list is on the Everolimus page.
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