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Interações medicamentosas

Ginko biloba + Ketorolac

Gravidade: Grave

Ginko biloba and Ketorolac: major interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.

O que esta interação significa em palavras simples

Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Ginko biloba belongs to Gastrointestinal Tract; Ketorolac belongs to Musculoskeletal.

Nível de evidência: Low

Por que acontece

Additive antiplatelet effects: ginkgolides antagonize platelet-activating factor while ketorolac strongly inhibits COX-1-mediated thromboxane production.

O que fazer

Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.

O que perguntar ao farmacêutico

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Ginko biloba with Ketorolac?

MediHelp rates the interaction as major. Ginko biloba and Ketorolac can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ketorolac is a potent NSAID with marked antiplatelet effect and a labeled bleeding warning, and ginkgo biloba adds further antiplatelet activity. Together they may substantially raise the risk of serious bleeding, including gastrointestinal and perioperative hemorrhage.

How serious is the interaction between Ginko biloba and Ketorolac?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ginkgo during ketorolac therapy and stop it before surgery or procedures with bleeding risk. Monitor for bleeding if the combination has been taken.

What other medicines interact with Ginko biloba?

MediHelp also lists interactions of Ginko biloba with, for example, Abciximab, Aceclofenac, Acemetacin. The full list is on the Ginko biloba page.

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