Interações medicamentosas
Measles mumps and rubella vaccine + Melphalan
Gravidade: Contraindicada
Measles mumps and rubella vaccine and Melphalan: contraindicated interaction.
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Resumo
Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
O que esta interação significa em palavras simples
Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Melphalan belongs to Oncology.
Por que acontece
Cytotoxic immunosuppression permits uncontrolled replication of live attenuated virus.
O que fazer
Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicada
- Anakinra + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicada
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicada
- Azathioprine + Measles mumps and rubella vaccine Contraindicada
- Basiliximab + Measles mumps and rubella vaccine Contraindicada
Outras interações de Melphalan
- Adenovirus types 4 and 7 live + Melphalan Contraindicada
- Bcg vaccine live + Melphalan Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Melphalan Contraindicada
- Measles mumps and rubella vaccine live + Melphalan Contraindicada
- Measles mumps rubella and varicella vaccine live + Melphalan Contraindicada
- Measles vaccine + Melphalan Contraindicada
Perguntas frequentes
Can I take Measles mumps and rubella vaccine with Melphalan?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
How serious is the interaction between Measles mumps and rubella vaccine and Melphalan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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