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Interações medicamentosas

Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil

Gravidade: Contraindicada

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

O que esta interação significa em palavras simples

Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: High

Por que acontece

Mycophenolate-induced lymphocyte suppression permits replication of live attenuated viruses.

O que fazer

Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

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Perguntas frequentes

Can I take Measles mumps rubella and varicella vaccine live with Mycophenolate mofetil?

MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.

How serious is the interaction between Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.

What other medicines interact with Mycophenolate mofetil?

MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.

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