Interações medicamentosas
Measles vaccine + Mycophenolate mofetil
Gravidade: Contraindicada
Measles vaccine and Mycophenolate mofetil: contraindicated interaction.
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Resumo
Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
O que esta interação significa em palavras simples
Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Impaired T and B cell function allows uncontrolled replication of live attenuated virus.
O que fazer
Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicada
- Bcg vaccine live + Mycophenolate mofetil Contraindicada
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicada
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicada
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicada
- Mycophenolate mofetil + Rotavirus oral vaccine live Contraindicada
Perguntas frequentes
Can I take Measles vaccine with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles vaccine and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated and can cause disseminated vaccine-strain infection in patients with significant immunosuppression. Mycophenolate may also reduce the immune response.
How serious is the interaction between Measles vaccine and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the vaccine during mycophenolate therapy. Give it at least 4 weeks before starting treatment if possible, and use immunoglobulin prophylaxis after exposure.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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