Interações medicamentosas
Methylprednisolone + Rubella vaccine
Gravidade: Contraindicada
Methylprednisolone and Rubella vaccine: contraindicated interaction.
Última atualização Fontes: US FDA label
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Resumo
Rubella vaccine is live attenuated, and immunosuppressive methylprednisolone doses may permit vaccine-virus replication and diminish immunogenicity.
O que esta interação significa em palavras simples
Methylprednisolone and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Corticosteroid-induced suppression of cellular immunity reduces control of live attenuated virus.
O que fazer
Avoid during immunosuppressive steroid doses and defer until the washout period recommended locally has passed. Low-dose or short-course therapy generally does not preclude vaccination.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Referências
Outras interações de Methylprednisolone
- Bcg vaccine live + Methylprednisolone Contraindicada
- Measles mumps and rubella vaccine live + Methylprednisolone Contraindicada
- Measles mumps rubella and varicella vaccine live + Methylprednisolone Contraindicada
- Measles vaccine + Methylprednisolone Contraindicada
- Methylprednisolone + Mifepristone Contraindicada
- Methylprednisolone + Smallpox vaccine live Contraindicada
Perguntas frequentes
Can I take Methylprednisolone with Rubella vaccine?
MediHelp rates the interaction as contraindicated. Methylprednisolone and Rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rubella vaccine is live attenuated, and immunosuppressive methylprednisolone doses may permit vaccine-virus replication and diminish immunogenicity.
How serious is the interaction between Methylprednisolone and Rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during immunosuppressive steroid doses and defer until the washout period recommended locally has passed. Low-dose or short-course therapy generally does not preclude vaccination.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.
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