Interações medicamentosas
Oxymorphone + Selegiline transdermal
Gravidade: Contraindicada
Oxymorphone and Selegiline transdermal: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
MAO inhibitors have been associated with serious reactions with opioids, including serotonin syndrome, hypotension, hyperpyrexia and CNS depression. Oxymorphone labeling advises against use with MAOIs.
O que esta interação significa em palavras simples
Oxymorphone and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
MAO inhibition may potentiate opioid effects and serotonergic or adrenergic toxicity; mechanism with oxymorphone is not fully defined.
O que fazer
Avoid concurrent use and for at least 14 days after stopping the MAOI. Choose an alternative analgesic.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Oxymorphone
- Alvimopan + Oxymorphone Contraindicada
- Ethanol + Oxymorphone Contraindicada
- Isocarboxazid + Oxymorphone Contraindicada
- Olanzapine / samidorphan + Oxymorphone Contraindicada
- Oxymorphone + Phenelzine Contraindicada
- Oxymorphone + Sodium oxybate Contraindicada
Perguntas frequentes
Can I take Oxymorphone with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Oxymorphone and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAO inhibitors have been associated with serious reactions with opioids, including serotonin syndrome, hypotension, hyperpyrexia and CNS depression. Oxymorphone labeling advises against use with MAOIs.
How serious is the interaction between Oxymorphone and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and for at least 14 days after stopping the MAOI. Choose an alternative analgesic.
What other medicines interact with Oxymorphone?
MediHelp also lists interactions of Oxymorphone with, for example, Alvimopan, Ethanol, Isocarboxazid. The full list is on the Oxymorphone page.
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