Лекарственные взаимодействия
Bcg vaccine live + Deflazacort
Тяжесть: Противопоказано
Bcg vaccine live and Deflazacort: contraindicated interaction.
Последнее обновление
Для специалистов здравоохранения — только для справки. Эта страница — краткая сводка, а не медицинская консультация и не замена официальной инструкции или клинического суждения. Всегда проверяйте перед назначением или отпуском.
Клиническое содержание этой страницы доступно только на английском языке.
Кратко
Deflazacort suppresses cellular immunity, so the live attenuated BCG organism may replicate unchecked and cause local or disseminated BCG infection. Vaccine response may also be blunted, leaving the patient inadequately protected.
Что означает это взаимодействие простыми словами
Bcg vaccine live and Deflazacort are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Glucocorticoid-induced immunosuppression impairs control of the live attenuated organism and reduces the immune response to the vaccine.
Что делать
Do not give BCG to patients on immunosuppressive doses of deflazacort; defer vaccination until corticosteroid therapy has been stopped for the interval stated in the product labeling. Use an alternative preventive strategy if protection is needed urgently.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Для подписчиков Pro+
Откройте страницу целиком
Создайте аккаунт и начните пробный период Pro+, чтобы открыть полные рекомендации по ведению для Bcg vaccine live и Deflazacort, дополнительные примечания, подробности о доказательной базе и проверку взаимодействий для всего рецепта.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ бесплатно 14 дней на сайте. Карта не нужна.
Другие взаимодействия Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Противопоказано
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Противопоказано
- Deflazacort + Measles mumps and rubella vaccine Противопоказано
- Deflazacort + Measles mumps and rubella vaccine live Противопоказано
- Deflazacort + Measles mumps rubella and varicella vaccine live Противопоказано
- Deflazacort + Measles vaccine Противопоказано
Частые вопросы
Can I take Bcg vaccine live with Deflazacort?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Deflazacort are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Deflazacort suppresses cellular immunity, so the live attenuated BCG organism may replicate unchecked and cause local or disseminated BCG infection. Vaccine response may also be blunted, leaving the patient inadequately protected.
How serious is the interaction between Bcg vaccine live and Deflazacort?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on immunosuppressive doses of deflazacort; defer vaccination until corticosteroid therapy has been stopped for the interval stated in the product labeling. Use an alternative preventive strategy if protection is needed urgently.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
