Лекарственные взаимодействия
Deflazacort + Measles mumps and rubella vaccine
Тяжесть: Противопоказано
Deflazacort and Measles mumps and rubella vaccine: contraindicated interaction.
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Кратко
Deflazacort given chronically is immunosuppressive, and live attenuated vaccines such as measles, mumps, rubella and varicella can replicate unchecked in an immunosuppressed host. This can cause vaccine-strain disease, and the immune response to the vaccine is also reduced.
Что означает это взаимодействие простыми словами
Deflazacort and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Deflazacort belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Почему это происходит
Corticosteroid immunosuppression permits live-vaccine replication and impairs response
Что делать
Avoid live vaccines during deflazacort therapy at immunosuppressive doses and for at least 4 weeks (ideally per specialist guidance) after stopping; complete live vaccinations at least 4 weeks before starting if possible.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Противопоказано
- Anakinra + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Противопоказано
- Azathioprine + Measles mumps and rubella vaccine Противопоказано
- Basiliximab + Measles mumps and rubella vaccine Противопоказано
Другие взаимодействия Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Противопоказано
- Bcg vaccine live + Deflazacort Противопоказано
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Противопоказано
- Deflazacort + Measles mumps and rubella vaccine live Противопоказано
- Deflazacort + Measles mumps rubella and varicella vaccine live Противопоказано
- Deflazacort + Measles vaccine Противопоказано
Частые вопросы
Can I take Deflazacort with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Deflazacort given chronically is immunosuppressive, and live attenuated vaccines such as measles, mumps, rubella and varicella can replicate unchecked in an immunosuppressed host. This can cause vaccine-strain disease, and the immune response to the vaccine is also reduced.
How serious is the interaction between Deflazacort and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during deflazacort therapy at immunosuppressive doses and for at least 4 weeks (ideally per specialist guidance) after stopping; complete live vaccinations at least 4 weeks before starting if possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
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