Лекарственные взаимодействия
Lomustine + Measles vaccine
Тяжесть: Противопоказано
Lomustine and Measles vaccine: contraindicated interaction.
Последнее обновление
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Кратко
Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
Что означает это взаимодействие простыми словами
Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
Что делать
Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Lomustine
- Adenovirus types 4 and 7 live + Lomustine Противопоказано
- Bcg vaccine live + Lomustine Противопоказано
- Influenza virus vaccine quadrivalent intranasal + Lomustine Противопоказано
- Lomustine + Measles mumps and rubella vaccine Противопоказано
- Lomustine + Measles mumps and rubella vaccine live Противопоказано
- Lomustine + Measles mumps rubella and varicella vaccine live Противопоказано
Частые вопросы
Can I take Lomustine with Measles vaccine?
MediHelp rates the interaction as contraindicated. Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
How serious is the interaction between Lomustine and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
