Лекарственные взаимодействия
Lomustine + Measles mumps and rubella vaccine live
Тяжесть: Противопоказано
Lomustine and Measles mumps and rubella vaccine live: contraindicated interaction.
Последнее обновление
Для специалистов здравоохранения — только для справки. Эта страница — краткая сводка, а не медицинская консультация и не замена официальной инструкции или клинического суждения. Всегда проверяйте перед назначением или отпуском.
Клиническое содержание этой страницы доступно только на английском языке.
Кратко
The live MMR vaccine can cause disseminated vaccine-virus infection in patients immunosuppressed by lomustine, and the antibody response may be poor.
Что означает это взаимодействие простыми словами
Lomustine and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
Что делать
Do not give during lomustine therapy; defer until immune recovery, generally at least 3 months after stopping. Check immunity serologically afterwards if needed.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Для подписчиков Pro+
Откройте страницу целиком
Создайте аккаунт и начните пробный период Pro+, чтобы открыть полные рекомендации по ведению для Lomustine и Measles mumps and rubella vaccine live, дополнительные примечания, подробности о доказательной базе и проверку взаимодействий для всего рецепта.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ бесплатно 14 дней на сайте. Карта не нужна.
Другие взаимодействия Lomustine
- Adenovirus types 4 and 7 live + Lomustine Противопоказано
- Bcg vaccine live + Lomustine Противопоказано
- Influenza virus vaccine quadrivalent intranasal + Lomustine Противопоказано
- Lomustine + Measles mumps and rubella vaccine Противопоказано
- Lomustine + Measles mumps rubella and varicella vaccine live Противопоказано
- Lomustine + Measles vaccine Противопоказано
Частые вопросы
Can I take Lomustine with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Lomustine and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live MMR vaccine can cause disseminated vaccine-virus infection in patients immunosuppressed by lomustine, and the antibody response may be poor.
How serious is the interaction between Lomustine and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give during lomustine therapy; defer until immune recovery, generally at least 3 months after stopping. Check immunity serologically afterwards if needed.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
