Лекарственные взаимодействия
Lomustine + Measles mumps rubella and varicella vaccine live
Тяжесть: Противопоказано
Lomustine and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
Последнее обновление
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Кратко
The combined live MMRV vaccine carries a risk of disseminated vaccine-strain infection in patients immunosuppressed by lomustine, and immunogenicity is reduced.
Что означает это взаимодействие простыми словами
Lomustine and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Почему это происходит
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
Что делать
Avoid during lomustine therapy and until immune recovery, generally at least 3 months after treatment. Revaccinate once immune function is restored.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Lomustine
- Adenovirus types 4 and 7 live + Lomustine Противопоказано
- Bcg vaccine live + Lomustine Противопоказано
- Influenza virus vaccine quadrivalent intranasal + Lomustine Противопоказано
- Lomustine + Measles mumps and rubella vaccine Противопоказано
- Lomustine + Measles mumps and rubella vaccine live Противопоказано
- Lomustine + Measles vaccine Противопоказано
Частые вопросы
Can I take Lomustine with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Lomustine and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The combined live MMRV vaccine carries a risk of disseminated vaccine-strain infection in patients immunosuppressed by lomustine, and immunogenicity is reduced.
How serious is the interaction between Lomustine and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during lomustine therapy and until immune recovery, generally at least 3 months after treatment. Revaccinate once immune function is restored.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
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