Лекарственные взаимодействия
Measles mumps and rubella vaccine + Oxaliplatin
Тяжесть: Противопоказано
Measles mumps and rubella vaccine and Oxaliplatin: contraindicated interaction.
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Кратко
Oxaliplatin-based chemotherapy causes myelosuppression and immune suppression, so the response to the live vaccine may be reduced. Replication of the vaccine viruses may be uncontrolled, which can cause serious vaccine-strain disease.
Что означает это взаимодействие простыми словами
Measles mumps and rubella vaccine and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Oxaliplatin belongs to Oncology.
Почему это происходит
Cytotoxic chemotherapy suppresses immune function, which blunts vaccine response and permits replication of live attenuated virus.
Что делать
Do not give MMR during chemotherapy; give it at least 2 to 4 weeks before starting if feasible. After completion, delay vaccination for about 3 months and until immune recovery.
О чём спросить фармацевта
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Другие взаимодействия Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Противопоказано
- Anakinra + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Противопоказано
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Противопоказано
- Azathioprine + Measles mumps and rubella vaccine Противопоказано
- Basiliximab + Measles mumps and rubella vaccine Противопоказано
Другие взаимодействия Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Противопоказано
- Bcg vaccine live + Oxaliplatin Противопоказано
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Противопоказано
- Measles mumps and rubella vaccine live + Oxaliplatin Противопоказано
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Противопоказано
- Measles vaccine + Oxaliplatin Противопоказано
Частые вопросы
Can I take Measles mumps and rubella vaccine with Oxaliplatin?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Oxaliplatin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oxaliplatin-based chemotherapy causes myelosuppression and immune suppression, so the response to the live vaccine may be reduced. Replication of the vaccine viruses may be uncontrolled, which can cause serious vaccine-strain disease.
How serious is the interaction between Measles mumps and rubella vaccine and Oxaliplatin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give MMR during chemotherapy; give it at least 2 to 4 weeks before starting if feasible. After completion, delay vaccination for about 3 months and until immune recovery.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Полные монографии, дозировки и проверка взаимодействий в приложении MediHelp
Откройте полный справочник, проверяйте взаимодействия нескольких препаратов и пользуйтесь инструментами дозирования в приложении MediHelp.
