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藥品參考

Atacicept

Atacicept is a medicine in the class miscellaneous. It is used for nephropathy.

最後更新 來源: US FDA label

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Miscellaneous
常見劑型
注射劑
常見規格
150 mg
商品名
1
國家與市場
1

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

TACI-Fc fusion glycoprotein that binds BAFF (BLyS) and APRIL, reducing BAFF- and APRIL-mediated signaling and decreasing production of galactose-deficient IgA1 (Gd-IgA1), which is implicated in IgAN.

成人常用劑量(仿單摘要)

Primary IgA nephropathy (to reduce proteinuria): 150 mg subcutaneously once weekly

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies.
哺乳
Unknown No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.

已通報的副作用

  • Infections
  • Upper respiratory tract infection
  • Local administration reactions
  • Injection site reaction
  • Injection site erythema

禁忌症

  • Serious hypersensitivity to atacicept-vymj or any excipients.

哪些人需要特別留意

  • Immunosuppression and increased risk of infections: assess for active infection before starting, monitor during treatment, and consider interruption for serious infection.
  • Concomitant use with other immune-modulating drugs, including systemic corticosteroids, may increase infection risk; combined use has not been evaluated.
  • May interfere with vaccine responses; complete immunizations before starting; live vaccines not recommended within 30 days before or during treatment.

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Atacicept 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • How to give it
  • Pharmacokinetics
  • Patient counselling points

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常見問題

What is Atacicept used for?

Atacicept is a medicine in the class miscellaneous. It is used for Nephropathy.

What side effects have been reported with Atacicept?

Infections, Upper respiratory tract infection, Local administration reactions, Injection site reaction, Injection site erythema.

Can Atacicept be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Human data insufficient to assess risk. Based on its mechanism it may suppress immunity in the exposed infant. No malformations in mouse or rabbit studies. Breastfeeding: Unknown. No data on milk levels or infant effects. As a large protein, infant absorption is likely low. Weigh breastfeeding benefits against the mother's need.

What does Atacicept interact with?

MediHelp does not list a checked interaction for Atacicept yet. Always tell your pharmacist about every medicine you take.

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