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藥品參考

Rupatadine

Rupatadine is a medicine in the class respiratory. It is used for allergic rhinitis.

最後更新 來源: Health Canada product monograph, UK SmPC

僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

重點資訊

藥物類別
Respiratory
常見劑型
錠劑, 糖漿
常見規格
10 mg, 1 mg/ml
商品名
9
國家與市場
2

劑型、規格與商品名稱會因國家而異。請核對您手上的產品。

用途

作用方式

Rupatadine is a second-generation antihistamine, long-acting histamine antagonist, with selective peripheral H1-receptor antagonist activity. Some of the metabolites (desloratadine and its hydroxylated metabolites) retain an antihistaminic activity and may partially contribute to the overall efficacy of the drug.

成人常用劑量(仿單摘要)

Adults and adolescents (over 12 years of age): The recommended dose is 10 mg (one tablet) once a day, with or without food.

僅摘錄仿單中第一行劑量說明;完整的劑量內容請見 App。

懷孕與哺乳

懷孕
Unknown Limited human data; no harm in animal studies. UK label: as a precaution, preferably avoid in pregnancy. Loratadine or cetirizine are the preferred antihistamines in pregnancy.
哺乳
Unknown Not known if it passes into milk (found in animal milk). UK label: decide whether to stop breastfeeding or the drug. LactMed: two breastfed infants had no effects, but one mother on a double dose had falling milk supply; an alternative may be preferred. Watch for drowsiness.

已通報的副作用

  • Abnormal liver function
  • Alanine aminotransferase increased
  • Cough
  • Constipation
  • Back pain
  • Dry mouth

禁忌症

  • Hypersensitivity to rupatadine or any ingredient in the formulation or component of the container.
  • History of QT prolongation and/or torsade de pointes, including congenital long QT syndromes, or history of cardiac arrhythmias.
  • Use of CYP3A4 inhibitors or other QTc-prolonging drugs.

哪些人需要特別留意

  • Due to the presence of lactose monohydrate in rupatadine 10 mg tablets, patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.
  • Contraindicated in children under 2 years
  • Not all formulations are suitable for use in children under 12 years

請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏,以及您正在使用的所有其他藥物或保健品。

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可開啟 Rupatadine 的完整藥品專論:劑量、懷孕與哺乳、副作用、警示及所有交互作用。

  • Dosing by age, kidney and liver function, and further dose lines
  • Renal and hepatic dose adjustments
  • Paediatric dosing
  • Dosing in older adults
  • How to give it
  • Pharmacokinetics
  • Patient counselling points
  • Food interactions

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同類別的其他藥品

常見問題

What is Rupatadine used for?

Rupatadine is a medicine in the class respiratory. It is used for Allergic rhinitis, Urticaria.

What side effects have been reported with Rupatadine?

Abnormal liver function, Alanine aminotransferase increased, Cough, Constipation, Back pain, Dry mouth.

Can Rupatadine be taken in pregnancy or while breastfeeding?

Pregnancy: Unknown. Limited human data; no harm in animal studies. UK label: as a precaution, preferably avoid in pregnancy. Loratadine or cetirizine are the preferred antihistamines in pregnancy. Breastfeeding: Unknown. Not known if it passes into milk (found in animal milk). UK label: decide whether to stop breastfeeding or the drug. LactMed: two breastfed infants had no effects, but one mother on a double dose had falling milk supply; an alternative may be preferred. Watch for drowsiness.

What does Rupatadine interact with?

MediHelp does not list a checked interaction for Rupatadine yet. Always tell your pharmacist about every medicine you take.

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