藥品參考
Sibeprenlimab
Sibeprenlimab is a medicine in the class miscellaneous. It is used for nephropathy.
- 藥物類別: Miscellaneous
- 用途: nephropathy
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Miscellaneous
- 常見劑型
- 注射劑
- 常見規格
- 200 mg/ml
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Binds APRIL with a KD of 0.95 pM, blocking signaling at BCMA and TACI receptors. Inhibiting APRIL reduces serum galactose-deficient IgA1 (Gd-IgA1), which is implicated in the pathogenesis of IgAN.
成人常用劑量（仿單摘要）
Primary IgA nephropathy at risk for progression (reduce proteinuria): 400 mg, subcutaneous injection, once every 4 weeks
懷孕與哺乳
- 懷孕
- Unknown No human data. Monoclonal antibodies cross the placenta, mostly in the second and third trimesters. A monkey ePPND study showed no adverse embryofetal or postnatal effects at about 10-times clinical exposure.
- 哺乳
- Unknown No data on presence in human milk or effects on the infant or milk production. Weigh the benefits of breastfeeding against the mother's clinical need and potential adverse effects on the infant.
已通報的副作用
- Infections
- Injection site reactions
- Upper respiratory tract infection
- Injection site erythema
禁忌症
- Serious hypersensitivity to sibeprenlimab-szsi or any excipients.
哪些人需要特別留意
- Immunosuppression and increased infection risk: assess for active infection before starting and monitor during treatment. Patients with chronic or recurring infections may be at higher risk of serious infection.
- Limited data with concomitant systemic immunosuppressants; consider the potential for increased immunosuppression.
- Live vaccines are not recommended within 30 days before starting or during treatment; may interfere with vaccine responses.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
Pro+ 會員專屬
解鎖完整頁面
建立帳號並開始 Pro+ 試用，即可開啟 Sibeprenlimab 的完整藥品專論：劑量、懷孕與哺乳、副作用、警示及所有交互作用。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
在網頁版免費試用 Pro+ 14 天，無需信用卡。
同類別的其他藥品
常見問題
What is Sibeprenlimab used for?
Sibeprenlimab is a medicine in the class miscellaneous. It is used for Nephropathy.
What side effects have been reported with Sibeprenlimab?
Infections, Injection site reactions, Upper respiratory tract infection, Injection site erythema.
Can Sibeprenlimab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data. Monoclonal antibodies cross the placenta, mostly in the second and third trimesters. A monkey ePPND study showed no adverse embryofetal or postnatal effects at about 10-times clinical exposure. Breastfeeding: Unknown. No data on presence in human milk or effects on the infant or milk production. Weigh the benefits of breastfeeding against the mother's clinical need and potential adverse effects on the infant.
What does Sibeprenlimab interact with?
MediHelp does not list a checked interaction for Sibeprenlimab yet. Always tell your pharmacist about every medicine you take.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
